Master parcours Structural and functional biochemistry

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Secrétariat pédagogique
M1 BT
METENIER Denise
denise.metenier@univ-tlse3.fr

M2 BT-SFB
METENIER Denise
denise.metenier@univ-tlse3.fr
Contacts internationaux
WALTERS Adam
fsi-contact.relations-internationales@univ-tlse3.fr
Contacts formation continue
CRESSAULT Yann
fsi-contact.formation-continue@univ-tlse3.fr
Responsable(s) de la formation
M1 BT
TROPIS Maryelle
tropis@ipbs.fr

M2 BT-SFB
ALBENNE Cecile
cecile.albenne@univ-tlse3.fr

DUMAS Fabrice
dumas@ipbs.fr

Composante

Détails

Infos clés

Composante

Lieu(x) des enseignements

  • Toulouse - 118 rte de Narbonne

  • All teaching are provided on the UT3 campus site.

Niveau d'admission

  • Bac + 3

Niveau de sortie

  • Bac + 5 (Niveau I)

Stage(s)

Oui, obligatoire(s)

Les +

Domaine(s) de compétence

  • Sciences du vivant
  • Santé et soins

Langue(s) d'enseignement

  • Anglais

Aménagement(s)

  • Etudiant en situation de handicap
  • Etudiant entrepreneur
  • Etudiant salarié
  • Sportif et Artiste de haut niveau

Rythme et modalités d’enseignement

Accessible en
  • Formation initiale
  • Formation continue / FTLV
  • VAE
  • Présentiel

Présentation de la formation

2nd year of master Structural and Fuctional Biochemistry
Our objective is to give you a solid, thorough training in the art of thinking: clear reasoning, critical analysis, deciphering complex subjects, and techniques such as conveying your thoughts accurately.
Our goal is to produce graduates with detailed knowledge of molecular mechanisms in Biology applied to pharmacology, structural biology, cellular biophysics or biotechnology.
Graduating students will thereby gain an unique perspective on biological problems through their contribution to scientific research projects.

[u]Technological workshop[/u]
Students will follow lectures and practicals on cutting-edge techniques. A list of 5 categories of techniques is proposed: molecular biology, structural biology of macromolecules, metabolomics, proteomics and biophysics. Student will be asked to choose 3 of these and will receive 50 hours of practical and lectures of each. This will allow students to adapt their formation to their professional goals.
Students will receive theoretical and technical training on most commonly used in the following fields:
  • Molecular biology: study of the different methods used in molecular biology, This module willbe mainly based on the analysis of "Matherial and Methods" of recently published papers, Student will be asked to find alternatives methods and to discuss results.
  • Biophysics: super-resolution fluorescence microscopy, Small-angle X-ray scattering, calorimetry, circular dichroism, electron microscopy, atomic force microscopy (AFM), analytic ultracentrifugation.
  • Proteomics: Ionization modes (ESI, MALDI), scanning modes (TOF, q-TOF, Orbitrap…), strategies of analysis (bottom-up, top-down/middle-down), study of postraductional modifications of proteins and interactomes using mass spectrometry, informatics data treatment.
  • Structural biology of macromolecules: 2D and 3D NMR; X-ray crystallography, electronic microscopy, molecular modelization.
  • Metabolomics: This course covers modern research on metabolism and is orientated to systems approaches in metabolic research. As well as acquiring an in-depth understanding of modern principles in metabolism, students will develop skills in methods (metabolomics, fluxomics) to investigate metabolism at the system level

[u]Thematic Workshop[/u]
This teaching unit will depend on the professional project of each student:
  • For students aiming at pursuing their studies by a PhD degree, students will have to create a thesis project starting from 3 to 4 published papers on a specific theme. These themes will be related to the main topics of the master (Structural Biology, Proteomics, Biophysics, Metabolomics, Molecular Biology...) and will change every year. Each student will have to create a thesis project under the supervision of teachers and researches specialised in the domain. The thesis project will be evaluated according the rules of the Doctoral School of Toulouse ""BSB"" (10 minutes of presentation and 15 minutes of questions).
  • For students whose project is to apply for a job as an engineer in a technological facility (proteomic or metabolomic) or in industry, the content will focus on practical courses covering the complete metabolomic or proteomic workflow thanks to access to Toulouse facilities' modern equipment. Students will have to produce reports on these practical works. Students will also have to prepare literature-based reviews on specific topics selected from their internship projects and to assist to seminars on metabolomics or proteomics.

[u]Statistics and knowledge of companies[/u]
Basic courses describing the organization and management of companies.
All students will receive 10 hours of formation on statistics applied to biology.
Another part will be devoted to fictive job interviews (individual trainings with a professional from human resources).

[u]Internship[/u]
Students will participate to a scientific project, by taking part to a research program or by contributing to a technological development using innovative instruments devoted to structural biochemistry. The internship could be realised either in a public lab or in a company, in France or abroad.
At the end of the training, strudents will have to present their projects and results through a written report and on oral presentation.

Connaissances

  • Moleculat biology.
  • Proteomics.
  • Metabolomics.
  • Biophysics.
  • Structural biology of macromolecules.
  • Statistics.
  • Basics on managment.

Lieu(x) des enseignements

Toulouse - 118 rte de Narbonne

Durée de la formation

2 ans

Admission

Pré-requis

Niveau(x) de recrutement

Bac + 3

Formation(s) requise(s)

Licence mention Sciences de la Vie, parcours 2B2M (Biochimie - Biologie Moléculaire - Microbiologie).
Cheminement :
  • L1 Sciences de la Vie.
  • L2 Biochimie - Biologie Moléculaire - Microbiologie (2B2M).
  • L3 Biochimie - Biologie Moléculaire - Microbiologie (2B2M).

Modalités de candidature

Les formations de Master sont ouvertes aux titulaires des diplômes sanctionnant les études du premier cycle (180 ECTS) ou équivalent et dans un domaine d’études correspondant. L’admission est prononcée à l’issue d’une procédure de sélection et en fonction des capacités d’accueil définies par l’établissement. Le dépôt des candidatures doit être effectué sur le site e-candidat (voir Candidater).

Modalités de candidature spécifiques

https://www.univ-tlse3.fr/candidatures

Programme

Le syllabus de chacune des années composant le diplôme est téléchargeable au format PDF. Le document comporte une présentation de l’année, le programme de chacune des Unités d’Enseignement (UE) avec la bibliographie associée ainsi que les coordonnées de l’enseignant responsable et du secrétariat de la formation.

During the internship, students will participate to a scientific project, by taking part to a research program or by contributing to a technological development using innovative instruments devoted to structural biochemistry. The internship could be realised either in a public lab or in a company, in France or abroad in a field related to the scope of the master 2 (structural biology, biotechnologies, biophysics, omics...).
At the end of the training, strudents will have to present their projects and results through a written report and on oral presentation.

The internship last 6 months between January and September.

Non

Et après ?

Compétences

  • Represent the structure of biomolecules (proteins, lipids, nucleic acids, carbohydrates ...), to deduce their physico-chemical and biological properties, to predict intra- and inter-molecular interactions;
  • Recognize and analyze the main metabolic pathways and their interconnections;
  • Use and adapt molecular genetics and genomics / transcriptomics technologies for the study and the modification of microorganisms;
  • Design and implement an experimental strategy to answer a research question or test a scientific hypothesis
  • Conduct a project alone or with a team
  • Interpret and model experimental results using mathematical, statistical and / or computer tools and querying the data banks of protein and nucleotide sequences and structures;
  • Write and present in English (oral and written) a scientific project or report of a bibliographic or experimental research activity.

Poursuites d'études

À l’UT3

Doctorat dans les Ecoles Doctorales Biologie-Santé-Biotechnologies (BSB) et Sciences Ecologiques, Vétérinaires, Agronomiques, Bio-ingénieries (SEVAB).

Débouchés professionnels

Secteur(s) d’activité(s)

  • Biotechnologie.
  • Santé humaine et animale.

Métiers

  • Cadre de recherche et développement.
  • Cadre de laboratoire.
  • Chef de projet.
  • Chargé(e) de mission.
  • Chargé(e) d'étude.
  • Ingénieur(e) d'étude.
  • Communication scientifique.

Devenir des diplômés

Enquête OVE

Interrogés 30 mois après l’obtention de leur diplôme, les diplômés répondent à des questions concernant notamment leur premier emploi et leur situation actuelle (emploi, poursuite d’études, etc.).
Téléchargez les résultats