Master parcours Biomolecular sciences: mechanisms and therapeutic targets (BSM2T)


International program based on a solid training in structural and functional biochemistry. Students will be offered theoretical and technical training in most of the cutting-edge techniques in this field. Lectures are provided in English language.

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Secrétariat pédagogique

Contacts internationaux
Contacts formation continue
Responsable(s) de la formation
BOUSQUET Marie-Pierre

NIETO Laurence


BOUSQUET Marie-Pierre

NIETO Laurence



Infos clés


Lieu(x) des enseignements

  • Toulouse - 118 rte de Narbonne

  • All teaching are provided on the UT3 campus site.

Niveau d'admission

  • Bac + 3

Niveau de sortie

  • Bac + 5 (Niveau 7)


Oui, obligatoire(s) (attributif ECTS)

Les +

Domaine(s) de compétence

  • Sciences du vivant
  • Santé et soins

Langue(s) d'enseignement

  • Anglais

Aménagement(s) des études

  • Etudiant en situation de handicap
  • Etudiant entrepreneur
  • Etudiant salarié
  • Sportif et Artiste de haut niveau

Rythme et modalités d’enseignement

Accessible en
  • Alternance
    • Contrat d'apprentissage
    • Contrat de professionnalisation
  • Formation initiale
  • Formation continue / FTLV
  • VAE
  • Présentiel
En savoir plus à propos du Accessible en

Présentation de la formation

Ce parcours de master comprend deux années (60 ECTS chacune).
Première année (M1) : Syllabus du M1 biotechnologies

The 2nd year (M2) is an international Master's degree program based on a solid training in structural and functional biochemistry. Students will be offered theoretical and technical training in most of the cutting-edge techniques in this field. Lectures will be provided in English language.
Students will be asked to select 3 courses among the 4 following items, in order to tailor their study program to suit their academic and career goals:
- Molecular biology & imaging: Principal aims in this course: i) to reinforce or to update your knowledge of the basic principles and methods used in molecular biology and imaging; to show you how to read, understand and analyze published articles concerning molecular biology topics. As it is a technical workshop, you will be asked to raise concerns regarding the experiments, to propose alternative techniques and to discuss the results presented in several publications.
- Integrative Structural biology of macromolecules: will provide you the conceptual and practical basis required to understand the current literature and will introduce you to the latest developments in the fields: advanced methodologies such as electron microscopy, X-ray crystallography, small angle X-ray scattering and nuclear magnetic resonance. It also requires a permanent use of computational biology, and the characterisation of interactions between molecules by biophysical methods such as ITC, microscale thermophoresis, SPR or DSF.
- Proteomics: Mass spectrometry-based approaches for global characterization of proteomes and interactomes, and structural exploration of proteins: Principle of mass spectrometry applied to proteins and peptides, basics of modern mass spectrometers, and presentation of the main workflows used in proteomic analysis (Bottom-up, top-down/middle-down, interactomics, Post-Translational Modifications, including sample preparation workflows).
- Metabolomics: in-depth understanding of the approaches (metabolomics, fluxomics) allowing the investigation of metabolism at the system level (from cells to whole organisms). NMR-based metabolomics & fluxomics. MS-Based metabolomics & fluxomics. The course includes lectures, exercises, and workshops on specific topics as well as illustrative examples of the application of metabolomics and fluxomics to address current challenges in Human health and in other major research fields.
Mandatory courses in Statistics, Bioethics, Scientific analysis and communication, and Basics of management will also be offered. In addition, students will have the opportunity to deepen their knowledge performing a scientific/technological project within the frame of academic or professional themes.
A full description of the Master program can be downloaded here (syllabus).


This Master's degree will allow students to acquire a solid background in the understanding of living system molecular mechanisms, as well as strong skills in the techniques currently used to identify molecules and/or to study their structure, function and interactions. Students will acquire a broad range of the different approaches and they will develop their critical thinking skill in solving biological issues.
Students will also benefit from a solid, thorough, and broad-based training in the art of thinking and presenting results through an extensive practice in clear reasoning, critical analysis, and deciphering complex subjects.
  • Moleculat biology.
  • Proteomics.
  • Metabolomics.
  • Biophysics.
  • Structural biology of macromolecules.
  • Statistics.
  • Basics on managment.

Lieu(x) des enseignements

Toulouse - 118 rte de Narbonne

Durée de la formation

2 ans



A Toulouse : Institut de Pharmacologie et de Biologie Structurale (IPBS), Centre de Biologie Intégrative (CBI), Centre de Recherche en Cancérologie de Toulouse (CRCT), Laboratoire de recherche en Sciences Végétales (LRSV), Institut Toulousain des Maladies Infectieuses et Inflammatoires (INFINITY), RESTORE...
Hors Toulouse : nombreux laboratoires CNRS, INSERM, INRA, CEA, Pasteur, Curie...


Evotec, Sanofi-Aventis, Pierre Fabre, Roche, Amatsi group, Norvartis, GTP Technology, Nestlé, Unilever, Galderma, Nanobiotix, Cargill, Imabiotech, Syngenta, Apteeus, Aspen Pharma, L'Oréal, Anaquant, Fournier



Niveau(x) de recrutement

Bac + 3

Formation(s) requise(s)

Admission in 2nd year (M2): Students originating from a first year of Master's in the area of Biochemistry, Biotechnology or Structural Biology from any University, are invited to apply. Admission to this master's degree is subject to the examination of an application by the faculty board and to an interview (on the campus or via visioconference). The number of seats is limited.
The criteria considered are the transcripts of the academic work (please provide these documents when applying) but also the motivation and personality of applicants.

Modalités de candidature

Les formations de Master sont ouvertes aux titulaires des diplômes sanctionnant les études du premier cycle (180 ECTS) ou équivalent et dans un domaine d’études correspondant. L’admission est prononcée à l’issue d’une procédure de sélection et en fonction des capacités d’accueil définies par l’établissement. Le dépôt des candidatures doit être effectué sur le site e-candidat (voir Candidater).


Le syllabus est téléchargeable au format PDF. Le document comporte une présentation de l’année, le programme de chacune des Unités d’Enseignement (UE) avec la bibliographie associée ainsi que les coordonnées de l’enseignant responsable et du secrétariat de la formation.

During the internship, students will participate in a scientific project, by taking part in a research program or by contributing to a technological development using innovative instruments devoted to structural biochemistry. The internship could take place either in a public lab or in a company, in France or abroad in a topic related to the field of the master 2 (structural biology, molecular biology and biotechnologies, biophysics, omics, physiopathology..).
At the end of the training, students will have to present their projects and their results through a written report and an oral presentation.
The internship lasts 6 months between January and September.

The internship lasts 6 months between January and September.

Students will have the opportunity to deepen their knowledge by performing a scientific/technological project within the frame of academic or professional themes


Les étudiants alternants seront intégrés dans le même groupe d'étudiants que les étudiants en formation initiale et suivront le même programme depuis début septembre jusqu'à mi-novembre. Ils réaliseront leur projet scientifique ou technologique au sein de leur laboratoire ou entreprise d'accueil, respectivement, ce qui leur permettra de rejoindre le milieu professionnel à partir de mi-novembre et jusqu'à fin août de l'année suivante. Ils seront tutorés à distance par un membre de l'équipe pédagogique.
Seule l'année de M2 est accessible à l'alternance et le contrat est généralement établi pour une année (à partir de début septembre et jusqu'à fin août de l'année suivante, mais ces dates peuvent être ajustées).

Et après ?


  • Design and implement an experimental strategy using modern approaches in molecular biology, imaging, metabolomics, proteomics, and structural biology, to answer a research question or test a scientific hypothesis;
  • Conduct a project alone, or within a team;
  • Critically analyze scientific articles in relation with cutting edge/hot topics in biology, and using techniques in the field of structural and functional biochemistry;
  • Interpret and model experimental results using statistical and/or computer tools and querying the data banks of protein and nucleotide sequences and structures;
  • Write and present in English language (written and oral scientific communication) a scientific project or a synthesis/report of a bibliographic or experimental research activity.

Poursuites d'études

À l’UT3

Pursuit for higher education - in UT3: PHD in Écoles Doctorales Biologie-Santé-Biotechnologies (BSB) et Sciences Ecologiques, Vétérinaires, Agronomiques, Bioingénieries (SEVAB).